It is now understood that inflammation is a key underlying cause of dry eye disease.
IPL utilizes light waves of specific wavelengths to shrink tiny blood vessels, which can thus suppress the leakage of proteins responsible for inflammation. By doing so, significant control over inflammation can be achieved with the corresponding improvement in symptoms of dry eye.
Furthermore, the thermal pulses can also help alleviate symptoms in some patients. In meibomian gland dysfunction, a state of chronic inflammation can result in a change in lipid composition. This change converts the oils to monounsaturated fatty acids, which increases the melting of the lipid to 45ºC, which is slightly higher than the normal body temperature of 37ºC. This makes the lipids assume a more solid form that can then easily clog the gland ducts.
When thermal pulses are applied to the tear glands, the heat and pressure from the pulsation can melt the lipids so that they form a part of the tear film as they normally should.
An alternative to IPL therapy is a manual expression of the meibomian glands, but this process is not as effective and is also quite uncomfortable.
Thus, by unclogging the meibomian gland, IPL therapy can be a non-invasive and comfortable alternative for treating dry eye diseases caused by meibomian gland dysfunction.